Department of Applied Biological Science (HP: English / 日本語)

Faculty of Science and Technology (HP: English / 日本語)

Tokyo University of Science (HP: English / 日本語)

© 2013 by Lab of Molecular Neuroscience.

   All rights reserved.

東京理科大学 理工学部 応用生物科学科

Publication

2019

Hosoi N., Shibasaki K., Hosono M., Konno A., Shinoda Y., Kiyonari H., Inoue K., Muramatsu S.-i., Ishizaki Y., Hirai H., Furuichi T., Sadakata T. Deletion of class II ADP-ribosylation factors in mice causes tremor by the Nav1.6 loss in cerebellar Purkinje cell axon initial segments. Journal of Neuroscience 39(32): 6339-6353, 2019.

Wada M., Ide M., Atsumi T., Sano Y., Shinoda Y., Furuichi T., Kansaku K. Rubber tail illusion is weakened in Ca2+-dependent activator protein for secretion 2 (Caps2)-knockout mice. Scientific Reports 9(1):7552, 2019.

Koebis M., Urata S., Shinoda Y., Okabe S., Yamasoba T., Nakao K., Aiba A., Furuichi T. LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing. Molecular Brain 12:20, 2019.

 

Shinoda Y., Sadakata T., Yagishita K., Kinameri E., Katoh-Semba R., Sano Y., Furuichi T. Aspects of excitatory/inhibitory synapses in multiple brain regions are correlated with levels of brain-derived neurotrophic factor/neurotrophin-3. Biochem. Biophys. Res. Commun. 509 (2):429-434, 2019.

 

Morita M, Shimokawa K, Nishimura M, Nakamura S, Tsujimura Y, Takemoto S, Tawara T, Yokota H, Wemler S, Miyamoto D, Ikeno H, Sato A, Furuichi T, Kobayashi N, Okumura Y, Yamaguchi Y, Okamura-Oho Y. ViBrism DB: an interactive search and viewer platform for 2D/3D anatomical images of gene expression and co-expression networks. Nucleic Acid Res. 47: Database issue, D859-D866, 2019.

2018

Shinoda Y, Sadakata T, Akagi T, Sakamaki Y, Hashikawa T, Sano Y, Furuichi T. Calcium-dependent activator protein for secretion 2 (CADPS2) deficiency causes abnormal synapse development in hippocampal mossy fiber terminals development in hippocampal mossy fiber terminals. Neurosci Lett. 677:65-71, 2018.

2017

Nakayama K., Ohashi R., Shinoda Y., Yamazaki M., Abe M., Fujikawa A., Shigenobu S., Futatsugi A., Noda M., Mikoshiba K., Furuichi T., Sakimura K., and Shiina N. RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation. eLife 6: e29677, 2017.

Yagishita K., Suzuki R., Mizuno S., Katoh-Semba R., Sadakata T., Sano Y., Furuichi T., Shinoda Y. CAPS2 deficiency affects environmental enrichment-induced adult neurogenesis and differentiation/survival of newborn neurons in the hippocampal dentate gyrus. Neuroscience Letters 661:121-125, 2017

Ihara D., Fukuchi M., Katakai M., Shinoda Y., Katoh-Semba R., Furuichi T., Ishikawa M., Tabuchi A., Tsuda M. Deltamethrin increases neurite outgrowth in cortical neurons through endogenous BDNF/TrkB pathways. Cell Structure and Function 42(2): 141-148, 2017

Hayashi K, Furuya A, Sakamaki Y, Akagi T, Shinoda Y, Sadakata T, Hashikawa T, Shimizu K, Minami H, Sano Y, Nakayama M, and Furuichi T. The brain-specific RasGEF very-KIND is required for normal dendritic growth in cerebellar granule cells and proper motor coordination. PLoS ONE 12(3):e0173175, 2017

Sadakata, T., Shinoda, Y., Ishizaki, Y., and Furuichi, T. Analysis of gene expression in Ca2+-dependent activator protein for secretion 2 (Cadps2) knockout cerebellum using GeneChip and KEGG pathways. Neurosci. Lett. 639:88-93, 2017

2016

Yoshikawa, F., Sato, Y., Tohyama, K., Akagi, T., Furuse, T., Sadakata, T., Tanaka, M., Shinoda, Y., Hashikawa, T., Itohara, S., Sano, Y., Ghandour, SM., Wakana, S., and Furuichi, T. Mammalian-specific central myelin protein Opalin is redundant for normal myelination: structural and behavioral assessments. PLoS ONE 11(11): e0166732, 2016

 

Shinoda, Y., Nakajima, Y., Iguchi, H., Tatsumi, S., Kitaoka, M., Nakajima, M., Takahashi, T., Fujiwara, M., and Furuichi, T. Galacto-N-biose is neuroprotective against glutamate-induced excitotoxicity in vitro. European Journal of Pharmacology 791: 711-717, 2016

 

Shinoda, Y., Ishii, C., Fukazawa, Y., Sadakata, T., Ishii, Y., Sano, Y., Iwasato, T., Itohara, S., and Furuichi, T. CAPS1 stabilizes the state of readily releasable synaptic vesicles to fusion competence at CA3–CA1 synapses in adult hippocampus. Scientific Reports 6:31540, 2016

Nakajima, Y., Iguchi, H., Kamisuki, S., Sugawara, F., Furuichi, T., Shinoda, Y. Low doses of the mycotoxin citrinin protect cortical neurons against glutamate-induced excitotoxicity. J. Toxicol. Sci., 41:311-319, 2016

 

Hosono, M., Shinoda, Y., Hirano, T., Ishizaki, Y., Furuichi, T., Sadakata, T. Interaction of Ca2+-dependent activator protein for secretion 1 (CAPS1) with septin family proteins in mouse brain. Neurosci. Lett. 617: 232–235, 2016

 

2015

Mishima Y, Shinoda Y, Sadakata T, Kojima M, Wakana S, Furuichi T.  Lack of stress responses to long-term effects of corticosterone in Caps2 knockout mice. Scientific Reports 5: 8932, 2015

 

2014

Okamura-Oho, Y., Shimokawa, K., Nishimura, M., Takemoto, S., Sato, A., Furuichi, T., and Yokota, H. Broad integration of expression maps and co-expression networks compassing novel gene functions in the brain. Scientific Reports 4:6969, 2014

 

Sato, Y., Yoshikawa, F., Sadakata, T., Shinoda, Y., Koebis, M., and Furuichi, T. Age-dependent redistribution and hypersialylation of the central myelin paranodal loop membrane protein Opalin in the mouse brain. Neurosci. Lett. 581: 14-19, 2014

 

Sadakata, T., Kakegawa, W., Shinoda, Y., Hosono, M., Katoh-Semba, R., Sekine, Y., Sato, Y., Saruta, C., Ishizaki, Y., Yuzaki, M., Kojima, M., and Furuichi, T. Axonal localization of Ca2+-dependent activator protein for secretion 2 is critical for subcellular locality of brain-derived neurotrophic factor and neurotrophin-3 release affecting proper development of postnatal mouse cerebellum. PLoS ONE 9(6): e99524, 2014

 

Tanabe, K., Yamazaki, H., Inaguma, Y., Asada, A., Kimura, T., Takahashi, J., Taoka, M., Ohshima T., Furuichi, T., Isobe, T., Nagata, K., Shirao, T., and Hisanaga, S. Phosphorylation of Drebrin by Cyclin-Dependent Kinase 5 and Its Role in Neuronal Migration. PLoS ONE 9(3): e92291, 2014

 

2013
Sadakata, T., Kakegawa, W., Shinoda, Y., Hosono, M., Katoh-Semba,R., Sekine, Y., Sato, Y., Tanaka, M., Iwasato, T., Itohara, S., Furuyama, K., Kawaguchi, Y., Ishizaki, Y., Yuzaki, M., and Furuichi, T. CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain. J. Neurosci., 33:17326-17334, 2013

 

Motoyoshi-Yamashiro A., Tamura M., Moriyama M., Takano K., Kawabe K., Nakajima H., Katoh-Semba R., Furuichi T., and Nakamura Y. Activation of cultured astrocytes by amphotericin B: Stimulation of NO and cytokines production and changes in neurotrophic factors. Neurochem. Int. 63:93-100, 2013

 

Shinoda Y, Sadakata T, Furuichi T. Animal Models of Autism Spectrum Disorder (ASD): A Synaptic-level Approach to Autistic-like Behavior in Mice. Exp. Anim. 62(2), 71-78, 2013

Tanaka M., Shih PY., Gomi H., Yoshida H., Nakai J., Ando R., Furuichi T., Mikoshiba K., Semyanov A., Itohara S. Astrocytic Ca2+ signals are required for the functional integrity of tripartite synapses. Mol. Brain 6:6, 2013

 

Sadakata, T., Shinoda, Y., Oka, M., Sekine, Y., and Furuichi, T. Autistic-like behavioral phenotypes in a mouse model with copy number variation of the CAPS2/CADPS2 gene. FEBS Lett. 587:54-59, 2013

 

Sadakata T, Shinoda Y, Sato A, Iguchi H, Ishii C, Matsuo M, Yamaga R, Furuichi T. Mouse models of mutations and variations in autism spectrum disorder-associated genes: mice expressing caps2/cadps2 copy number and alternative splicing variants. Int J Environ Res Public Health. 10(12):6335-6353, 2013

 

2012

Sadakata T., Shinoda, Y., Oka, M., Sekine, Y., Sato, Y., Saruta, C., Miwa, H., Tanaka, M., Itohara, S., and Furuichi, T. Reduced axonal localization of a Caps2 splice variant impairs axonal release of BDNF and causes autistic-like behavior in mice. Proc. Natl. Acad. Sci. U.S.A. 109:21104-21109, 2012


Fujita, H., Morita, N., Furuichi, T., and Sugiura, I. Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into postnatal striped configuration. J. Neurosci. 32:15688-15703, 2012


Sadakata, T., Sekine, Y., Oka, M., Itakura, M., and Furuichi, T. Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking. FEBS J. 279:384-394, 2012

2011

Otani, Y., Yamaguchi, Y., Sato, Y., Furuichi, T., Ikenaka, K., Kitani, H., and Baba, H. PLD4 is involved in phagocytosis of microglia: expression and localization changes of PLD4 are correlated with activation state of micrglia. PLoS One 6(11):e27544, 2011


Hamatake, M., Miyazaki, N., Sudo, K., Matsuda, M., Sadakata, T., Furuya, A., Ichisaka, S., Hata, Y., Nakagawa, C., Nagata, K., Furuichi, T., Katoh-Semba, R. Phase advance of the light-dark cycle perturbs diurnal rhythms of brain-derived neurotrophic factor and neurotrophin-3 protein levels, which reduces synaptophysin-positive presynaptic terminals in the cortex of juvenile rats. J. Biol. Chem. 286:21478-21487, 2011


Huang, J., Furuya, A., Hayashi, K., and Furuichi, T. Interaction between very-KIND RasGEF and MAP2, and its role in dendrite growth: structure and function of the second kinase non-catalytic C-lobe domain. FEBS J. 278:1651-1661, 2011


Shinoda, Y., Sadakata, T., Nakao, K., Katoh-Semba, R., Kinameri, E., Furuya, A., Yanagawa, Y., Hirase, H., and Furuichi, T. Calcium-dependent activator protein for secretion 2 (CAPS2) promotes BDNF secretion and is critical for the development of GABAergic interneuron network. Proc. Natl. Acad. Sci. U.S.A. 108:373-378, 2011


Masuya, H., Makita, Y., Kobayashi, N., Nishikata, K., Yoshida, Y., Mochizuki, Y., Doi, K., Takatsuki, T., Waki, K., Tanaka, K., Ishii, M., Matsushima, A., Takahashi, S., Mizoguchi, R., Kozaki, T., Furuichi, T., Kawaji, H., Wakana, S., Nakamura, Y., Yoshiki, A., Murata, T., Fukami-Kobayashi, K., Mohan, S., Ohara, O., Hayashizaki, Y., Obata, Y., and Toyoda, T. The RIKEN integrated database of mammals. Nucleic Acids Res. 39:D861-870, 2011

 

2010

Yoshikawa, F., Banno, Y., Otani, Y., Yamaguchi, Y., Nagakura-Takagi, Y., Morita, N., Sato, Y., Saruta, C., Nishibe, H., Sadakata, T., Shinoda, Y., Hayashi, K., Mishima, Y., Baba, H., and Furuichi, T. Phospholipase D Family Member 4, a Transmembrane Glycoprotein with no Phospholipase D activity, Expression in Spleen and Early Postnatal Microglia. PLoS ONE 5(11):e13932, 2010


Sadakata, T., Shinoda, Y., Sekine, Y., Saruta, C., Itakura, M., Takahashi, M., and Furuichi, T. Interaction of CAPS1 with the class II Arf small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network. J. Biol. Chem. 285:38710-38719, 2010


Furutama, D., Morita, N., Takano, R., Sekine, Y., Sadakata, T., Shinoda, Y., Hayashi, K., Mishima, Y., Mikoshiba, K., Hawkes, R., and Furuichi, T. Expression of the IP3R1 promoter-driven nls-lacZ transgene in Purkinje cell parasagittal arrays of developing mouse cerebellum. J. Neurosci. Res. 88:2810-2825, 2010

 

2009

Shiraishi-Yamaguchi, Y., Sato, Y., Sakai, R., Mizutani, A., Knopfel, T., Mori, N., Mikoshiba, K., and Furuichi, T. Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spines. BMC Neurosci. 10(1):25, 2009


Amano, K., Fujii, M., Arata, S., Tojima, T., Ogawa, M., Morita, N., Shimohata, A., Furuichi, T., Itohara, S., Kamiguchi, H., Korenberg, J.R., Arata, A., and Yamakawa, K. DSCAM deficiency causes loss of pre-inspiratory neuron synchroneity and perinatal death. J. Neurosci. 29:2984-2996, 2009

 

2008

Yoshikawa, F., Sato, Y., Tohyama, K., Akagi, T., Hashikawa, T., Nagakura-Takagi, Y., Sekine, Y., Morita, N., Baba, H., Suzuki, Y., Sugano, S., Sato, A., and Furuichi, T. Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane. J. Biol. Chem. 283:20830-20840, 2008


Mizutani, A., Kuroda, Y., Futatsugi, A., Furuichi, T., and Mikoshiba, K. Phosphorylation of Homer3 by calcium/calmodulin-dependent kinase II regulates a coupling state of its target molecules in Purkinje cells. J. Neurosci. 28:5369-5382, 2008


Suzuki, T., Inoue, I., Yamagata, T., Morita, N., Furuichi, T., and Yamakawa, K. Sequential expression of Efhc1/myoclonin1 in choroid plexus and ependymal cell cilia. Biochem. Biophys. Res. Commun. 367:226-233, 2008


Tsutsumi, K., Tomomura, M., Furuichi, T., and Hisanaga, S. Palmitoylation-dependent endosomal localization of AATYK1A and its interaction with Src. Genes to Cells 13:949-964, 2008

 

2007

Huang, J., Furuya, A., and Furuichi, T. Very-KIND, a KIND domain-containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2. J. Cell Biol. 179:539-552, 2007


Sadakata, T., Kakegawa, W., Mizoguchi, A., Washida, M., Katoh-Semba, R., Shutoh, F., Okamoto, T., Nakashima, H., Kimura, K., Tanaka, M., Sekine, Y., Itohara, S., Yuzaki, M., Nagao, S., and Furuichi, T. Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release. J. Neurosci. 27:2472-2482, 2007


Sadakata, T., Washida, M., Iwayama, Y., Shoji, S., Sato, Y., Ohkura, T., Kato-Semba, R., Nakajima, M., Sekine, Y., Tanaka, M., Nakamura, K., Iwata, Y., Tsuchiya, K.J., Mori, N., Detera-Wadleigh, S.D., Ichikawa, H., Itohara, S., Yoshikawa, T., and Furuichi, T. Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients. J. Clin. Invest. 117:931-943, 2007


Sadakata T, Washida M, and Furuichi T. Alternative splicing variations in mouse CAPS2: differential expression and functional properties of splicing variants. BMC Neurosci. 8:25, 2007


Sadakata, T., Washida, M., Morita, N., and Furuichi, T. Tissue distribution of Ca2+-dependent activator protein for secretion family members CAPS1 and CAPS2 in mice. J. Histochem. Cytochem. 55:301-311, 2007


Aruga, J., Yoshikawa, F., Nozaki, Y., Sakaki, Y., Toyoda, A., and Furuichi, T. An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin. J. Neurochem. 102:1533-1547, 2007


Tomomura, M., Morita, N., Yoshikawa, F., Konishi, A., Akiyama, H., Furuichi, T., and Kamiguchi, H.Structural and functional analysis of the apoptosis-associated tyrosine kinase (AATYK) family. Neurosci. 148:510-521, 2007


Ohnishi, T., Ohba, H., Seo, K.C., Im, J., Sato, Y., Iwayama, Y., Furuichi, T., Chung, S.K., and Yoshikawa, T. Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1. J. Biol. Chem. 282:637-646, 2007


Ajima, R., Kajiya, K., Inoue, T., Tani, M., Shiraishi-Yamaguchi, Y., Maeda, M., Segawa, T., Furuichi, T., Sutoh, K., and Yokota, J. HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growth. Biochem. Biophys. Res. Commun. 356:851-856, 2007


Ogiwara, I., Miyamoto, H., Morita, N., Atapour, N., Mazaki, E., Inoue, I., Takeuchi, T., Itohara, S., Yanagawa Y., Obata, K., Furuichi, T., Hensch, T.K., and Yamakawa, K. NaV1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J. Neurosci. 27:5903-5914, 2007


Kuwajima, M., Dehoff, M.H., Furuichi, T., Worley, P.F., Hall, R.A., and Smith, Y. Localization and expression of group I metabotropic glutamate receptors in the mouse striatum, globus pallidus, and subthalamic nucleus: regulatory effects of MPTP treatment and constitutive Homer deletion. J. Neurosci. 27:6249-6260, 2007

 

2006

Huang, J., Sakai, R., and Furuichi, T. The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons. Mol. Biol. Cell. 17:3187-3196, 2006


Sadakata, T., Itakura, M., Kozaki, S., Sekine, Y., Takahashi, M., and Furuichi, T. Differential distributions of the Ca2+-dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain. J. Comp. Neurol. 495:735-753, 2006


Sadakata, T. and Furuichi, T. Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain. Neurosci. Lett. 405:217-222, 2006


Kawano, S., Otsu, K., Kuruma, A., Shoji, S., Yanagida, E., Muto, Y., Yoshikawa, F., Hirayama, Y., Mikoshiba, K., and Furuichi, T. ATP autocrine/paracrine signaling induces calcium oscillations and NFAT activation in human mesenchymal stem cells. Cell Calcium 39:313-324, 2006


2005

Tomomura, M. and Furuichi, T. Apoptosis-associated tyrosine kinase (AATYK) has differential Ca2+-dependent phosphorylation states in response to survival and apoptotic conditions in cerebellar granule cells. J. Biol. Chem. 280:35157-35163, 2005


Matsuki, T., Hori, G., and Furuichi, T. Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system. Mol. Brain Res. 136:231-254, 2005


Iwai, M., Tateishi, Y., Hattori, M., Mizutani, A., Nakamura, T., Futatsugi, A., Inoue, T., Furuichi, T., Michikawa, T., and Mikoshiba, K. Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant. J. Biol. Chem. 280:10305-10317, 2005

2004

Sadakata, T., Mizoguchi, A., Sato, Y., Katoh-Semba, R., Fukuda, M., Mikoshiba, K., and Furuichi, T. The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. J. Neurosci. 24:43-52, 2004


Shiraishi, Y., Mizutani, A., Yuasa, S., Mikoshiba, K., and Furuichi, T. Differential expression of Homer family proteins in the developing mouse brain. J. Comp. Neurol. 473:582-599, 2004


Sato, Y., Shiraishi, Y., and Furuichi, T. Cell specificity and efficiency of the Semliki forest virus vector- and adenovirus vector-mediated gene expression in mouse cerebellum. J. Neurosci. Methods 137:111-121, 2004


Kakinuma, Y., Saito, F., Osawa, S., Furuichi, T., and Miura, M. A sulfatase regulating the migratory potency of oligodendrocyte progenitor cells through tyrosine phosphorylation of beta-catenin. J. Neurosci. Res. 77:653-661, 2004


Yanagida, E., Shoji, S., Hirayama, Y., Yoshikawa, F., Otsu, K., Uematsu, H., Hiraoka, M., Furuichi, T., and Kawano, S. Functional expression of Ca2+ signaling pathways in mouse embryonic stem cells. Cell Calcium 36:135-146, 2004


2003

Shiraishi, Y., Mizutani, A., Mikoshiba, K., and Furuichi, T. Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons. Mol. Cell. Neurosci. 22:188-201, 2003


Shiraishi, Y., Mizutani, A., Yuasa, S., Mikoshiba, K., and Furuichi, T. Glutamate-induced declustering of post-synaptic adaptor protein Cupidin (Homer2/vesl-2) in cultured cerebellar granule cells. J. Neurochem. 87:364-376, 2003


Uchida, K., Miyauchi, H., Furuichi, T., Michikawa, T., and Mikoshiba, K. Critical regions for activation gating of the inositol 1,4,5-trisphosphate receptor. J. Biol. Chem. 278:16551-16560, 2003


Tomomura, M., Hasegawa, Y., Hashikawa, T., Tomomura, A., Yuzaki, M., Furuichi, T., and Yano, R. Differential expression and function of apoptosis-associated tyrosine kinase (AATYK) in the developing mouse brain. Mol. Brain Res. 112:103-112, 2003

 

2002

Bosanac, I., Alattia, J.R., Mal, T.K., Chan, J., Talarico, S., Tong, F.K., Tong, K.I., Yoshikawa, F., Furuichi, T., Iwai, M., Michikawa, T., Mikoshiba, K., and Ikura, M. Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand. Nature 420:696-700, 2002


Iwasaki, H., Chiba, K., Uchiyama, T., Yoshikawa, F., Suzuki, F., Ikeda, M., Furuichi, T., and Mikoshiba, K. Molecular characterization of the starfish inositol 1,4,5-trisphosphate receptor and its role during oocyte maturation and fertilization. J. Biol. Chem. 277:2763-2772, 2002


Uchiyama, T., Yoshikawa, F., Hishida, A., Furuichi, T., and Mikoshiba, K. A novel recombinant hyperaffinity inositol 1,4,5-trisphosphate (IP3) absorbent traps IP3, resulting in specific inhibition of IP3-mediated calcium signaling. J. Biol. Chem. 277:8106-8113, 2002

 

2001

Kagami, Y., and Furuichi, T. Investigation of differentially expressed genes during the development of mouse cerebellum. Gene Expr. Patterns 1:39-59, 2001

 

1999

Shiraishi, Y., Mizutani, A., Bito, H., Fujisawa, K., Narumiya, S., Mikoshiba, K., and Furuichi, T. Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated Rho family small GTPases and is expressed in developing mouse cerebellar granule cells. J. Neurosci. 19:8389-8400, 1999


Michikawa, T., Hirota, J., Kawano, S., Hiraoka, M., Yamada, M., Furuichi, T., and Mikoshiba, K. Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol 1,4,5-trisphosphate receptor. Neuron 23:799-808, 1999


Hirota, J., Furuichi, T., and Mikoshiba, K. Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for Caspase-3 and is cleaved during apoptosis in a Caspase-3-dependent manner. J. Biol. Chem. 274:34433-34437, 1999


Baylis, H.A., Furuichi, T., Yoshikawa, F., Mikoshiba, K., and Sattelle, D.B. Inositol 1,4,5-trisphosphate receptors are strongly expressed in the nervous system, pharynx, intestine, gonad and excretory cell of Caenorhabditis elegans and are encoded by a single gene (itr-1). J. Mol. Biol. 294:467-476, 1999


Zhu, C.C., Furuichi, T., Mikoshiba, K., and Wojcikiewicz, R.J.H. Inositol 1,4,5-trisphosphate receptor down-regulation is activated directly by inositol 1,4,5-trisphosphate binding. J. Biol. Chem. 274:3476-3484, 1999


Yoshikawa, F., Iwasaki, H., Michikawa, T., Furuichi, T., and Mikoshiba, K. Trypsinized cerebellar inositol 1,4,5-trisphosphate receptor: structural and functional coupling of cleaved ligand binding and channel domains. J. Biol. Chem. 274:316-327, 1999


Yoshikawa, F., Iwasaki, H., Michikawa, T., Furuichi, T., and Mikoshiba, K. Cooperative formation of the ligand-binding site of the inositol 1,4,5-trisphosphate receptor by two separable domains. J. Biol. Chem. 274:328-334, 1999


Yoshikawa, F., Uchiyama, T., Iwasaki, H., Tomomori-Satoh, C., Tanaka, T., Furuichi, T., and Mikoshiba, K. High efficient expression of the functional ligand binding site of the inositol 1,4,5-trisphosphate receptor in Escherichia coli. Biochem. Biophys. Res. Commun. 257:792-797, 1999


Natsume, T., Hirota, J., Yohikawa, F., Furuichi, T., and Mikoshiba, K. Real time analysis of interaction between inositol 1,4,5-Trisphosphate receptor type 1 and its ligand. Biochem. Biophys. Res. Commun. 260:527-533, 1999


Konishi, Y., Ohkawa, N., Makino, Y., Okubo, H., Kageyama, R., Furuichi, T., Mikoshiba, K., and Tamura, T. Transcriptional regulation of mouse type 1 inositol 1,4,5-trisphosphate receptor gene by NeuroD-related factor. J. Neurochem. 72:1717-1724, 1999


Mitsuyama, F., Sawai, T., Carafoli, E., Furuichi, T., and Mikoshiba, K. Microinjection of Ca2+ store-enriched microsome fractions to dividing newt eggs induces extra-cleavage furrows via inositol 1,4,5-trisphosphate-induced Ca2+ release. Dev. Biol. 214:160-167, 1999


Hirota, J., Michikawa, T., Natsume, T., Furuichi, T., and Mikoshiba. K. Calmodulin inhibits inositol 1,4,5-trisphosphate-induced calcium release through the purified and reconstituted inositol 1,4,5-trisphosphate receptor type 1. FEBS Lett. 456:322-326, 1999